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PBX1 抗体 (AA 315-430) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-PBX1 antibody specifically detects PBX1 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7164138
发货至: 中国
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Quick Overview for PBX1 抗体 (AA 315-430) (Biotin) (ABIN7164138)

抗原

See all PBX1 抗体
PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

适用

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宿主

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克隆类型

  • 16
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多克隆

标记

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This PBX1 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

    • 5
    • 3
    • 2
    • 1
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    • 1
    • 1
    • 1
    AA 315-430

    原理

    PBX1 Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Pre-B-cell leukemia transcription factor 1 protein (315-430AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

    别名

    PBX1

    背景

    Background: Binds the sequence 5\'-ATCAATCAA-3\'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1,19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Probably in complex with MEIS2, is involved in transcriptional regulation by KLF4. Acts as a transcriptional activator of NKX2-5 and a transcriptional repressor of CDKN2B. Together with NKX2-5, it is required for spleen development through a mechanism that involves CDKN2B repression (By similarity).

    Aliases: DKFZp686B09108 antibody, Homeo box protein PBX1 antibody, Homeo box protein PRL antibody, Homeobox protein PBX 1 antibody, Homeobox protein PBX1 antibody, Homeobox protein PRL antibody, MGC126627 antibody, PBX 1 antibody, Pbx1 antibody, PBX1_HUMAN antibody, Pre B cell leukemia homeobox 1 antibody, Pre B cell leukemia transcription factor 1 antibody, Pre-B-cell leukemia transcription factor 1 antibody, PRL antibody

    UniProt

    P40424
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