EED 抗体 (AA 1-300)
Quick Overview for EED 抗体 (AA 1-300) (ABIN7163806)
抗原
See all EED 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-300
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Polycomb protein EED protein (1-300AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- EED (Embryonic Ectoderm Development (EED))
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别名
- EED
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背景
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Background: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates \\\'Lys-9\\\' and \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes \\\'Lys-26\\\' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 \\\'Lys-27\\\', whereas H3 \\\'Lys-27\\\' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Aliases: eed antibody, EED protein antibody, EED, mouse, homolog of antibody, EED_HUMAN antibody, Embryonic ectoderm development antibody, Embryonic ectoderm development isoform a antibody, Embryonic ECTODERM development protein homolog antibody, Embryonic ectoderm development protein, mouse, homolog of antibody, hEED antibody, OTTHUMP00000235483 antibody, OTTHUMP00000235484 antibody, OTTHUMP00000235485 antibody, Polycomb protein eed antibody, WAIT 1 antibody, WAIT-1 antibody, WAIT1 antibody, WD protein associating with integrin cytoplasmic tails 1 antibody
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UniProt
- O75530
抗原
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