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EED 抗体 (AA 1-300)

This 兔 多克隆 anti-EED antibody specifically detects EED in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7163806
发货至: 中国
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Quick Overview for EED 抗体 (AA 1-300) (ABIN7163806)

抗原

See all EED 抗体
EED (Embryonic Ectoderm Development (EED))

适用

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宿主

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克隆类型

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多克隆

标记

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This EED antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-300

    原理

    EED Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Polycomb protein EED protein (1-300AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    EED (Embryonic Ectoderm Development (EED))

    别名

    EED

    背景

    Background: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates \\\'Lys-9\\\' and \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes \\\'Lys-26\\\' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 \\\'Lys-27\\\', whereas H3 \\\'Lys-27\\\' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

    Aliases: eed antibody, EED protein antibody, EED, mouse, homolog of antibody, EED_HUMAN antibody, Embryonic ectoderm development antibody, Embryonic ectoderm development isoform a antibody, Embryonic ECTODERM development protein homolog antibody, Embryonic ectoderm development protein, mouse, homolog of antibody, hEED antibody, OTTHUMP00000235483 antibody, OTTHUMP00000235484 antibody, OTTHUMP00000235485 antibody, Polycomb protein eed antibody, WAIT 1 antibody, WAIT-1 antibody, WAIT1 antibody, WD protein associating with integrin cytoplasmic tails 1 antibody

    UniProt

    O75530
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