PCGF2 抗体 (AA 103-316) (Biotin)
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北京 101111
Quick Overview for PCGF2 抗体 (AA 103-316) (Biotin) (ABIN7163799)
抗原
See all PCGF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 103-316
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原理
- PCGF2 Antibody, Biotin conjugated
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Polycomb group RING finger protein 2 protein (103-316AA)
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亚型
- IgG
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anti-Polycomb Group Ring Finger 2 (PCGF2) (AA 236-294) antibody
PCGF2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D6 unconjugated
anti-Polycomb Group Ring Finger 2 (PCGF2) (AA 170-210) antibodyPCGF2 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 2 (PCGF2) (C-Term) antibodyVerified PCGF2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 2 (PCGF2) (AA 103-316) antibodyPCGF2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
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别名
- PCGF2
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背景
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Background: Transcriptional repressor. Binds specifically to the DNA sequence 5\'-GACTNGACT-3\'. Has tumor suppressor activity. May play a role in control of cell proliferation and/or neural cell development. Regulates proliferation of early T progenitor cells by maintaining expression of HES1. Also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \'Lys-119\', rendering chromatin heritably changed in its expressibility. Is not functionally redundant with BMI1, unlike BMI1 does not stimulate the E3 ubiquitin-protein ligase activity in a reconstituted PRC1-like complex (By similarity).
Aliases: DNA binding protein Mel 18 antibody, DNA-binding protein Mel-18 antibody, Mel 18 antibody, MGC10545 antibody, PCGF 2 antibody, PCGF2 antibody, PCGF2_HUMAN antibody, Polycomb group ring finger 2 antibody, Polycomb group RING finger protein 2 antibody, RING finger protein 110 antibody, RNF110 antibody, Zinc finger protein 144 antibody, ZNF 144 antibody, ZNF144 antibody
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UniProt
- P35227
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途径
- Chromatin Binding
抗原
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