PCGF1 抗体 (AA 113-187)
Quick Overview for PCGF1 抗体 (AA 113-187) (ABIN7163794)
抗原
See all PCGF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 113-187
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Polycomb group RING finger protein 1 protein (113-187AA)
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亚型
- IgG
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anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 105-187) antibody
PCGF1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 1-247) antibodyPCGF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 20-259) antibodyPCGF1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 121-220) antibodyPCGF1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 132-167) antibodyPCGF1 适用: 人 WB 宿主: 兔 Polyclonal RB51309 unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 117-151) antibodyPCGF1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB51308 unconjugated
anti-Polycomb Group Ring Finger 1 (PCGF1) (AA 143-192) antibodyPCGF1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PCGF1 (Polycomb Group Ring Finger 1 (PCGF1))
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别名
- PCGF1
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背景
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Background: Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6, this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down-regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \\\'Lys-119\\\', rendering chromatin heritably changed in its expressibility. Regulates the expression of DPPA4 and NANOG in the NT2 embryonic carcinoma cells (PubMed:26687479).
Aliases: PCGF1 antibody, NSPC1 antibody, RNF68 antibody, Polycomb group RING finger protein 1 antibody, Nervous system Polycomb-1 antibody, NSPc1 antibody, RING finger protein 68 antibody
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UniProt
- Q9BSM1
抗原
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