PUF60 抗体 (AA 302-413)
Quick Overview for PUF60 抗体 (AA 302-413) (ABIN7163781)
抗原
See all PUF60 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 302-413
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原理
- PUF60 Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Poly(U)-binding-splicing factor PUF60 protein (302-413AA)
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亚型
- IgG
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anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (C-Term) antibody
PUF60 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (AA 243-542) antibodyPUF60 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (C-Term) antibodyVerified PUF60 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) antibodyPUF60 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (AA 1-516) antibodyPUF60 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (C-Term) antibodyPUF60 适用: 人 WB, IHC (p), IF, ICC, IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (C-Term) antibodyPUF60 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (C-Term) antibodyPUF60 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 斑马鱼, 小鸡, 非洲爪蟾, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (AA 371-420) antibodyPUF60 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (AA 1-100) antibodyPUF60 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
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别名
- PUF60
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背景
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Background: DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Does not repress TFIIH-mediated transcription in xeroderma pigmentosum complementation group B (XPB) cells. Is also involved in pre-mRNA splicing. Promotes splicing of an intron with weak 3\\\'-splice site and pyrimidine tract in a cooperative manner with U2AF2. Involved in apoptosis induction when overexpressed in HeLa cells. Isoform 6 failed to repress MYC transcription and inhibited FIR-induced apoptosis in colorectal cancer. Isoform 6 may contribute to tumor progression by enabling increased MYC expression and greater resistance to apoptosis in tumors than in normal cells. Modulates alternative splicing of several mRNAs. Binds to relaxed DNA of active promoter regions. Binds to the pyrimidine tract and 3\\\'-splice site regions of pre-mRNA, binding is enhanced in presence of U2AF2. Binds to Y5 RNA in association with TROVE2. Binds to poly(U) RNA.
Aliases: 60 kDa poly(U)-binding-splicing factor antibody, FBP-interacting repressor antibody, FIR antibody, FLJ31379 antibody, FUSE-binding protein-interacting repressor antibody, Poly U binding splicing factor 60KDa antibody, Poly(U) binding splicing factor 60 antibody, Poly(U)-binding-splicing factor PUF60 antibody, poly-U binding splicing factor PUF60 antibody, PUF60 antibody, PUF60_HUMAN antibody, pyrimidine tract binding splicing factor antibody, Ro ribonucleoprotein-binding protein 1 antibody, Ro-binding protein 1 antibody, RoBP1 antibody, RoBPI antibody, siah binding protein 1 antibody, Siah-binding protein 1 antibody, Siah-BP1 antibody, SIAHBP1 antibody
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UniProt
- Q9UHX1
抗原
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