Plexin B2 抗体 (AA 1080-1200)
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北京 101111
Quick Overview for Plexin B2 抗体 (AA 1080-1200) (ABIN7163708)
抗原
See all Plexin B2 (PLXNB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1080-1200
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原理
- PLXNB2 Antibody
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交叉反应
- 小鼠
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Plexin-B2 protein (1080-1200AA)
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亚型
- IgG
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anti-Plexin B2 (PLXNB2) (AA 1458-1673) antibody
PLXNB2 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Plexin B2 (PLXNB2) (AA 1506-1611) antibodyPLXNB2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Plexin B2 (PLXNB2)
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别名
- PLXNB2
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背景
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Background: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \\\'Tyr-1248\\\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro) (By similarity).
Aliases: PLXNB2 antibody, KIAA0315 antibody, Plexin-B2 antibody, MM1 antibody
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UniProt
- O15031
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途径
- Tube Formation
抗原
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