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PAFAH1B1 抗体 (AA 40-155)

This anti-PAFAH1B1 antibody is a 兔 多克隆 antibody detecting PAFAH1B1 in ELISA 和 IF. Suitable for 人.
产品编号 ABIN7163601
发货至: 中国

Quick Overview for PAFAH1B1 抗体 (AA 40-155) (ABIN7163601)

抗原

See all PAFAH1B1 抗体
PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PAFAH1B1 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 40-155

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Platelet-activating factor acetylhydrolase IB subunit alpha protein (40-155AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))

    别名

    PAFAH1B1

    背景

    Background: Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position (By similarity). Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing.

    Aliases: LIS 1 antibody, LIS 2 antibody, LIS-1 antibody, LIS1 antibody, LIS1_HUMAN antibody, LIS2 antibody, Lissencephaly 1 protein antibody, Lissencephaly-1 protein antibody, MDCR antibody, MDS antibody, PAF acetylhydrolase 45 kDa subunit antibody, PAF AH 45 kDa subunit antibody, PAF AH alpha antibody, PAF-AH 45 kDa subunit antibody, PAF-AH alpha antibody, PAFAH alpha antibody, PAFAH antibody, PAFAH1B1 antibody, PAFAHA antibody, Platelet activating factor acetylhydrolase 1b regulatory subunit 1 antibody, Platelet activating factor acetylhydrolase isoform Ib alpha subunit antibody, Platelet-activating factor acetylhydrolase IB subunit alpha antibody

    UniProt

    P43034

    途径

    M Phase, Regulation of Cell Size
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