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PIWIL1 抗体 (AA 390-690)

This anti-PIWIL1 antibody is a 兔 多克隆 antibody detecting PIWIL1 in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7163477
发货至: 中国

Quick Overview for PIWIL1 抗体 (AA 390-690) (ABIN7163477)

抗原

See all PIWIL1 抗体
PIWIL1 (Piwi-Like 1 (PIWIL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PIWIL1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 15
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    AA 390-690

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Piwi-like protein 1 protein (390-690AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PIWIL1 (Piwi-Like 1 (PIWIL1))

    别名

    PIWIL1

    背景

    Background: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation. Probable component of some RISC complex, which mediates RNA cleavage and translational silencing. Also plays a role in the formation of chromatoid bodies and is required for some miRNAs stability (By similarity). Isoform 3 may be a negative developmental regulator (PubMed:12037681, PubMed:16287078).

    Aliases: HIWI antibody, MIWI antibody, Piwi (Drosophila) like 1 antibody, PIWI antibody, Piwi homolog antibody, Piwi like 1 (drosophila) antibody, Piwi like 1 antibody, Piwi-like protein 1 antibody, PIWIL1 antibody, PIWL1_HUMAN antibody

    UniProt

    Q96J94
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