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PHF1 抗体 (AA 151-360) (FITC)

This anti-PHF1 antibody is a 兔 多克隆 antibody detecting PHF1 in . Suitable for 人.
产品编号 ABIN7163044
发货至: 中国

Quick Overview for PHF1 抗体 (AA 151-360) (FITC) (ABIN7163044)

抗原

See all PHF1 抗体
PHF1 (PHD Finger Protein 1 (PHF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PHF1 antibody is conjugated to FITC

应用范围

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  • 抗原表位

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    AA 151-360

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human PHD finger protein 10 protein (151-360AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PHF1 (PHD Finger Protein 1 (PHF1))

    别名

    PHF1

    背景

    Background: Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).

    Aliases: BAF45a antibody, BRG1-associated factor 45a antibody, FLJ10975 antibody, MGC111009 antibody, PHD finger protein 10 antibody, PHD finger protein 10, isoform a antibody, PHD zinc finger protein XAP135 antibody, Phf10 antibody, PHF10_HUMAN antibody, XAP135 antibody

    UniProt

    Q8WUB8
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