PHF10 抗体 (AA 151-360)
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北京 101111
Quick Overview for PHF10 抗体 (AA 151-360) (ABIN7163042)
抗原
See all PHF10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-360
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原理
- PHF10 Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human PHD finger protein 10 protein (151-360AA)
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亚型
- IgG
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anti-PHD Finger Protein 10 (PHF10) antibody
PHF10 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PHD Finger Protein 10 (PHF10) (AA 1-410) antibodyPHF10 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-PHD Finger Protein 10 (PHF10) (AA 1-410) antibodyPHF10 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PHD Finger Protein 10 (PHF10) (AA 290-339) antibodyPHF10 适用: 人, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PHF10 (PHD Finger Protein 10 (PHF10))
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别名
- PHF10
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背景
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Background: Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Aliases: BAF45a antibody, BRG1-associated factor 45a antibody, FLJ10975 antibody, MGC111009 antibody, PHD finger protein 10 antibody, PHD finger protein 10, isoform a antibody, PHD zinc finger protein XAP135 antibody, Phf10 antibody, PHF10_HUMAN antibody, XAP135 antibody
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UniProt
- Q8WUB8
抗原
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