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ETHE1 抗体 (AA 8-254)

The 兔 多克隆 anti-ETHE1 antibody (ABIN7163017) specifically detects ETHE1 in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7163017
发货至: 中国
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Quick Overview for ETHE1 抗体 (AA 8-254) (ABIN7163017)

抗原

See all ETHE1 抗体
ETHE1 (Ethylmalonic Encephalopathy 1 (ETHE1))

适用

  • 41
  • 18
  • 3
  • 2
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  • 2

宿主

  • 39
  • 2

克隆类型

  • 41
多克隆

标记

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  • 1
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This ETHE1 antibody is un-conjugated

应用范围

  • 15
  • 13
  • 13
  • 9
  • 8
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 8-254

    原理

    ETHE1 Antibody

    交叉反应

    小鼠

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Persulfide dioxygenase ETHE1, mitochondrial protein (8-254AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ETHE1 (Ethylmalonic Encephalopathy 1 (ETHE1))

    别名

    ETHE1

    背景

    Background: Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus (PubMed:12398897).

    Aliases: Ethe1 antibody, ETHE1 protein, mitochondrial precursor antibody, ETHE1_HUMAN antibody, ethylmalonic encephalopathy 1 antibody, Ethylmalonic encephalopathy protein 1 antibody, hepatoma subtracted clone one antibody, Hepatoma subtracted clone one protein antibody, HSCO antibody, mitochondrial antibody, Protein ETHE1 antibody, Protein ETHE1 mitochondrial antibody, YF13H12 antibody

    UniProt

    O95571
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