PLIN5 抗体 (AA 305-453) (FITC)
Quick Overview for PLIN5 抗体 (AA 305-453) (FITC) (ABIN7162901)
抗原
See all PLIN5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 305-453
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Perilipin-5 protein (305-453AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PLIN5 (Perilipin 5 (PLIN5))
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别名
- PLIN5
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背景
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Background: Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity).
Aliases: Lipid storage droplet protein 5 antibody, LSDA5 antibody, MLDP antibody, OXPAT antibody, Perilipin 5 antibody, Perilipin-5 antibody, PLIN5 antibody, PLIN5_HUMAN antibody
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UniProt
- Q00G26
抗原
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