PCID2 抗体 (AA 2-250) (HRP)
Quick Overview for PCID2 抗体 (AA 2-250) (HRP) (ABIN7162713)
抗原
See all PCID2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-250
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human PCI domain-containing protein 2 protein (2-250AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PCID2 (PCI Domain Containing 2 (PCID2))
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别名
- PCID2
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背景
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Background: Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells.
Aliases: CSN12 like protein antibody, CSN12-like protein antibody, DKFZp686C20226 antibody, F10 antibody, FLJ11305 antibody, FLJ99362 antibody, HT004 antibody, MGC16774 antibody, PCI domain containing 2 antibody, PCI domain containing protein 2 antibody, PCI domain-containing protein 2 antibody, PCID2 antibody, PCID2_HUMAN antibody, RP11 - 98F14.6 antibody
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UniProt
- Q5JVF3
抗原
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