电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TERT 抗体 (pSer1125)

This anti-TERT antibody is a 兔 多克隆 antibody detecting TERT in WB, ELISA, FACS 和 IF (cc). Suitable for 人 和 小鼠.
产品编号 ABIN712046
发货至: 中国

Quick Overview for TERT 抗体 (pSer1125) (ABIN712046)

抗原

See all TERT 抗体
TERT (Telomerase Reverse Transcriptase (TERT))

适用

  • 106
  • 39
  • 25
  • 5
  • 1
  • 1
人, 小鼠

宿主

  • 114
  • 8
  • 1

克隆类型

  • 104
  • 19
多克隆

标记

  • 62
  • 8
  • 7
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This TERT antibody is un-conjugated

应用范围

  • 71
  • 49
  • 41
  • 26
  • 22
  • 17
  • 14
  • 13
  • 12
  • 10
  • 7
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

    • 16
    • 16
    • 10
    • 9
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1125

    交叉反应

    人, 小鼠

    预测反应

    Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human TERT around the phosphorylation site of Ser1125

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    TERT (Telomerase Reverse Transcriptase (TERT))

    别名

    TERT

    背景

    Synonyms: p-TERTSer1125, TERTphospho S1125, EST2, hEST2, TCS1, Telomerase associated protein 2, Telomerase Catalytic Subunit, Telomere Reverse Transcriptase, TERT, TP2, TRT.

    Background: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Telomerase are large DNA-protein complexes with telomerase expression being the subject of recent research due to its link to cell immortalization. Recent evidence has shown that MYC upregulates the catalytic subunit of telomerase, TERT, and that TERT cooperates with HPV E7 in cell immortalization. Ever since the discovery that telomeres are short in cancer cells and telomerase is activated in immortal cells, telomerase has been associated with oncogenes. During the past year, major advances have been made in understanding the link between telomerase expression and cell immortality. Studies of yeast telomeres have revealed an unexpected role for the non-homologous end-joining machinery in telomere maintenance and have provided the first definitive evidence that telomeres play a critical role in meiosis. Identification of new telomere proteins has led to a better understanding of vertebrate telomere structure and function.

    基因ID

    7015

    途径

    Telomere Maintenance
You are here:
Chat with us!