SIN3B 抗体 (AA 705-769) (Biotin)
Quick Overview for SIN3B 抗体 (AA 705-769) (Biotin) (ABIN7162488)
抗原
See all SIN3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 705-769
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Paired amphipathic helix protein Sin3b protein (705-769AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))
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别名
- SIN3B
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背景
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Background: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.
Aliases: SIN3B antibody, KIAA0700 antibody, Paired amphipathic helix protein Sin3b antibody, Histone deacetylase complex subunit Sin3b antibody, Transcriptional corepressor Sin3b antibody
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UniProt
- O75182
抗原
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