TRIP13 抗体 (AA 181-390)
Quick Overview for TRIP13 抗体 (AA 181-390) (ABIN7162475)
抗原
See all TRIP13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-390
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Pachytene checkpoint protein 2 homolog protein (181-390AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))
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别名
- TRIP13
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背景
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Background: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed:28553959).
Aliases: 16E1-BP antibody, 16E1BP antibody, Homo sapiens HPV16 E1 protein binding protein mRNA complete cds antibody, HPV16 E1 protein binding protein antibody, HPV16 E1 protein-binding protein antibody, Human papillomavirus type 16 E1 protein binding protein antibody, Human papillomavirus type 16 E1 protein-binding protein antibody, Pachytene checkpoint protein 2 homolog antibody, PCH2 antibody, Thyroid hormone receptor interactor 13 antibody, Thyroid receptor interacting protein 13 antibody, Thyroid receptor-interacting protein 13 antibody, TR-interacting protein 13 antibody, TRIP-13 antibody, Trip13 antibody, TRP13_HUMAN antibody
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UniProt
- Q15645
抗原
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