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OLR1 抗体 (AA 58-273)

This anti-OLR1 antibody is a 兔 多克隆 antibody detecting OLR1 in WB, IHC, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7162378
发货至: 中国

Quick Overview for OLR1 抗体 (AA 58-273) (ABIN7162378)

抗原

See all OLR1 抗体
OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

适用

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宿主

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克隆类型

  • 58
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多克隆

标记

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This OLR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 58-273

    交叉反应

    人, 大鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Oxidized low-density lipoprotein receptor 1 protein (58-273AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000, IF:1:200-1:500,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

    别名

    OLR1

    背景

    Background: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.

    Aliases: C-type lectin domain family 8 member A antibody, CLEC8A antibody, hLOX 1 antibody, hLOX-1 antibody, Lectin like oxidized LDL receptor 1 antibody, Lectin like oxLDL receptor 1 antibody, Lectin type oxidized LDL receptor 1 antibody, Lectin-like oxidized LDL receptor 1 antibody, Lectin-like oxLDL receptor 1 antibody, Lectin-type oxidized LDL receptor 1 antibody, low density lipoprotein oxidized, receptor 1 antibody, LOX-1 antibody, LOXIN antibody, Olr1 antibody, OLR1_HUMAN antibody, Ox LDL receptor 1 antibody, Ox-LDL receptor 1 antibody, Oxidised low density lipoprotein (lectin like) receptor 1 antibody, Oxidized low density lipoprotein receptor 1 antibody, Oxidized low density lipoprotein receptor 1 soluble form antibody, Oxidized low-density lipoprotein receptor 1 antibody, OxLDL receptor 1 antibody, SCARE1 antibody, Scavenger receptor class E, member 1 antibody, SLOX1 antibody, soluble form antibody, SR-EI antibody

    UniProt

    P78380
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