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NUMBL 抗体 (AA 447-576)

NUMBL 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7162085
发货至: 中国
  • 抗原 See all NUMBL 抗体
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    抗原表位
    • 15
    • 9
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    AA 447-576
    适用
    • 46
    • 9
    • 9
    • 1
    宿主
    • 44
    • 1
    • 1
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 11
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUMBL antibody is un-conjugated
    应用范围
    • 32
    • 21
    • 15
    • 13
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Numb-like protein (447-576AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    别名
    NUMBL (NUMBL 产品)
    别名
    nbl antibody, numb antibody, cag3a antibody, ctg3a antibody, numbr antibody, numb-r antibody, tnrc23 antibody, numblike antibody, CAG3A antibody, CTG3a antibody, NBL antibody, NUMB-R antibody, NUMBLIKE antibody, NUMBR antibody, TNRC23 antibody, NUMB like, endocytic adaptor protein antibody, numb homolog-like L homeolog antibody, NUMB-like, endocytic adaptor protein antibody, numb-like antibody, NUMBL antibody, numbl.L antibody, Numbl antibody
    背景

    Background: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the \\\'Lys-48\\\'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.

    Aliases: CAG 3A antibody, CAG3A antibody, CTG 3a antibody, CTG3a antibody, NBL antibody, NUMB Drosophilia Homolog Like antibody, Numb homolog (Drosophila) like antibody, Numb homolog like antibody, Numb like protein antibody, NUMB R antibody, Numb-like protein antibody, Numb-R antibody, Numb-related gene antibody, Numb-related protein antibody, NUMBL antibody, NUMBL_HUMAN antibody, NUMBLIKE antibody, NUMBR antibody, TNRC 23 antibody, TNRC23 antibody, Trinucleotide repeat-containing gene 23 antibody

    UniProt
    Q9Y6R0
    途径
    Cell-Cell Junction Organization
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