NME4 抗体 (AA 1-187)
Quick Overview for NME4 抗体 (AA 1-187) (ABIN7162056)
抗原
See all NME4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-187
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Nucleoside diphosphate kinase, mitochondrial protein (1-187AA)
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亚型
- IgG
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anti-NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4) (AA 1-187) antibody
NME4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4) antibodyNME4 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4) (AA 99-187) antibodyNME4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B6 unconjugated
anti-NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4) (AA 1-30), (N-Term) antibodyNME4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4055-4056 unconjugated
anti-NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4) antibodyNME4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4) (AA 107-156) antibodyNME4 适用: 人, Cow, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4) (AA 1-187) antibodyNME4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4) (AA 67-185) antibodyNME4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4) (AA 39-172) antibodyNME4 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4) (AA 158-187), (C-Term) antibodyNME4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4058 unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NME4 (NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4))
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别名
- NME4
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背景
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Background: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Through the catalyzed exchange of gamma-phosphate between di- and triphosphonucleosides participates in regulation of intracellular nucleotide homeostasis (PubMed:10799505). Binds to anionic phospholipids, predominantly to cardiolipin, the binding inhibits its phosphotransfer activity (PubMed:18635542, PubMed:23150663). Acts as mitochondria-specific NDK, its association with cardiolipin-containing mitochondrial inner membrane is coupled to respiration suggesting that ADP locally regenerated in the mitochondrion innermembrane space by its activity is directly taken up via ANT ADP/ATP translocase into the matrix space to stimulate respiratory ATP regeneration (PubMed:18635542). Proposed to increase GTP-loading on dynamin-related GTPase OPA1 in mitochondria (PubMed:24970086). In vitro can induce liposome cross-linking suggesting that it can cross-link inner and outer membranes to form contact sites, and promotes intermembrane migration of anionic phosphoplipids. Promotes the redistribution of cardiolipin between the mitochondrial inner membrane and outer membrane which is implicated in pro-apoptotic signaling (PubMed:18635542, PubMed:17028143, PubMed:23150663).
Aliases: metastatic inhibition factor NM23H4 antibody, mitochondrial antibody, NDK antibody, NDKM_HUMAN antibody, NDP kinase antibody, NDP kinase D antibody, NDP kinase, mitochondrial antibody, NDPK D antibody, NDPKD antibody, nm23 H4 antibody, nm23-H4 antibody, NM23D antibody, NM23H4 antibody, Nm23M4 antibody, NME/NM23 nucleoside diphosphate kinase 4 antibody, NME4 antibody, Non metastatic cells 4 protein expressed in antibody, Non metastatic protein 23, homolog 4 antibody, Nucleoside diphosphate kinase D antibody, Nucleoside diphosphate kinase, mitochondrial antibody, Nucleoside diphosphate kinase, mitochondrial antibody
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UniProt
- O00746
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途径
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
抗原
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