NCOA6 抗体 (AA 285-504) (Biotin)
Quick Overview for NCOA6 抗体 (AA 285-504) (Biotin) (ABIN7161866)
抗原
See all NCOA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 285-504
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Nuclear receptor coactivator 6 protein (285-504AA)
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亚型
- IgG
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anti-Nuclear Receptor Coactivator 6 (NCOA6) (AA 1954-2063) antibody
NCOA6 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Nuclear Receptor Coactivator 6 (NCOA6) (AA 285-504) antibodyNCOA6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))
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别名
- NCOA6
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背景
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Background: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.
Aliases: NCOA6 antibody, AIB3 antibody, KIAA0181 antibody, RAP250 antibody, TRBP antibody, Nuclear receptor coactivator 6 antibody, Activating signal cointegrator 2 antibody, ASC-2 antibody, Amplified in breast cancer protein 3 antibody, Cancer-amplified transcriptional coactivator ASC-2 antibody, Nuclear receptor coactivator RAP250 antibody, NRC RAP250 antibody, Nuclear receptor-activating protein antibody, 250 kDa antibody, Peroxisome proliferator-activated receptor-interacting protein antibody, PPAR-interacting protein antibody, PRIP antibody, Thyroid hormone receptor-binding protein antibody
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UniProt
- Q14686
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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