NMRAL1 抗体 (AA 1-299) (FITC)
Quick Overview for NMRAL1 抗体 (AA 1-299) (FITC) (ABIN7161663)
抗原
See all NMRAL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-299
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human NmrA-like family domain-containing protein 1 protein (1-299AA)
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亚型
- IgG
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anti-NmrA-Like Family Domain Containing 1 (NMRAL1) (AA 1-299) antibody
NMRAL1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-NmrA-Like Family Domain Containing 1 (NMRAL1) (AA 1-299) antibodyNMRAL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-NmrA-Like Family Domain Containing 1 (NMRAL1) (AA 216-265) antibodyNMRAL1 适用: 人, 大鼠, Cow, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-NmrA-Like Family Domain Containing 1 (NMRAL1) (N-Term) antibodyNMRAL1 适用: 大鼠, 小鼠, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-NmrA-Like Family Domain Containing 1 (NMRAL1) (Middle Region) antibodyNMRAL1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
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别名
- NMRAL1
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背景
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Background: Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.
Aliases: FLJ25918 antibody, HSCARG antibody, NmrA like family domain containing 1 antibody, NmrA like family domain containing protein 1 antibody, NmrA-like family domain-containing protein 1 antibody, NMRAL1 antibody, NMRL1_HUMAN antibody, SDR48A1 antibody
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UniProt
- Q9HBL8
抗原
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