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TNIK 抗体 (pSer764) (Biotin)

This anti-TNIK antibody is a 兔 多克隆 antibody detecting TNIK in ELISA, IHC (p) 和 IHC (fro). Suitable for 小鼠 和 大鼠.
产品编号 ABIN711943
发货至: 中国

Quick Overview for TNIK 抗体 (pSer764) (Biotin) (ABIN711943)

抗原

See all TNIK 抗体
TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TNIK antibody is conjugated to Biotin

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    pSer764

    特异性

    Phosphorylation site corresponds to Ser735 in mouse

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human TNIK around the phosphorylation site of Ser764

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

    别名

    TNIK

    背景

    Synonyms: TRAF2 and NCK-interacting protein kinase, TNIK, KIAA0551

    Background: Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.

    基因ID

    23043

    UniProt

    Q9UKE5
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