ULBP2 抗体 (AA 26-216)
Quick Overview for ULBP2 抗体 (AA 26-216) (ABIN7161653)
抗原
See all ULBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-216
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human NKG2D ligand 2 protein (26-216AA)
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亚型
- IgG
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anti-UL16 Binding Protein 2 (ULBP2) (AA 26-216) antibody
ULBP2 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1F12C2 unconjugated
anti-UL16 Binding Protein 2 (ULBP2) (AA 1-246) antibodyULBP2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-UL16 Binding Protein 2 (ULBP2) (AA 26-246) antibodyULBP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 2 (ULBP2) (AA 88-116) antibodyULBP2 适用: 人 WB 宿主: 兔 Polyclonal RB37009 unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ULBP2 (UL16 Binding Protein 2 (ULBP2))
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别名
- ULBP2
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背景
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Background: Ligand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
Aliases: ALCAN alpha antibody, ALCAN-alpha antibody, N2DL 2 antibody, N2DL-2 antibody, N2DL2 antibody, N2DL2_HUMAN antibody, NKG2D ligand 2 antibody, NKG2D ligand 2 precursor antibody, NKG2DL2 antibody, RAET1H antibody, Retinoic acid early transcript 1 H antibody, Retinoic acid early transcript 1H antibody, UL16 binding protein 2 antibody, UL16-binding protein 2 antibody, ULBP2 antibody
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UniProt
- Q9BZM5
抗原
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