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NPRL2 抗体 (AA 1-220)

This anti-NPRL2 antibody is a 兔 多克隆 antibody detecting NPRL2 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7161635
发货至: 中国

Quick Overview for NPRL2 抗体 (AA 1-220) (ABIN7161635)

抗原

See all NPRL2 抗体
NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))

适用

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宿主

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克隆类型

  • 50
多克隆

标记

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This NPRL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-220

    交叉反应

    人, 小鼠

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Nitrogen permease regulator 2-like protein (1-220AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))

    别名

    NPRL2

    背景

    Background: Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at \\\'Tyr-9\\\', \\\'Tyr-373\\\' and \\\'Tyr-376\\\' residues. May act as a tumor suppressor. Suppresses cell growth and enhances sensitivity to various anticancer drugs. As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.

    Aliases: 2810446G01Rik antibody, G21 protein antibody, Gene 21 protein antibody, Homologous to yeast nitrogen permease (candidate tumor suppressor) antibody, Homologous to yeast nitrogen permease antibody, Nitrogen permease regulator 2-like protein antibody, Nitrogen permease regulator-like 2 (S. cerevisiae) antibody, NPR 2L antibody, NPR L2 antibody, NPR like 2 antibody, NPR2 antibody, NPR2 like antibody, NPR2-like protein antibody, NPR2L antibody, NPRL 2 antibody, NPRL2 antibody, NPRL2_HUMAN antibody, Tumor suppressor candidate 4 antibody, TUSC 4 antibody, TUSC 4 protein antibody, TUSC4 antibody, TUSC4 protein antibody

    UniProt

    Q8WTW4
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