ASAH2 抗体 (AA 255-506)
Quick Overview for ASAH2 抗体 (AA 255-506) (ABIN7161486)
抗原
See all ASAH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 255-506
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交叉反应
- 人, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Neutral ceramidase protein (255-506AA)
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亚型
- IgG
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anti-N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2) (C-Term) antibody
ASAH2 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2) antibodyASAH2 适用: 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2) (AA 80-340) antibodyASAH2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2) (AA 734-762) antibodyASAH2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
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别名
- ASAH2
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背景
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Background: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
Aliases: Acylsphingosine deacylase 2 antibody, AI585898 antibody, ASAH2 antibody, ASAH2_HUMAN antibody, BCDase antibody, hCD antibody, HNAC1 antibody, LCDase antibody, MGC129777 antibody, mitochondrial ceramidase antibody, N acylsphingosine amidohydrolase (non lysosomal ceramidase) 2 antibody, N acylsphingosine amidohydrolase 2 antibody, N CDase antibody, N-acylsphingosine amidohydrolase 2 antibody, N-CDase antibody, NCDase antibody, Neutral ceramidase soluble form antibody, Non lysosomal ceramidase antibody, Non-lysosomal ceramidase antibody
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UniProt
- Q9NR71
抗原
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