NPAS4 抗体 (AA 445-585) (FITC)
Quick Overview for NPAS4 抗体 (AA 445-585) (FITC) (ABIN7161392)
抗原
See all NPAS4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 445-585
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Neuronal PAS domain-containing protein 4 protein (445-585AA)
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亚型
- IgG
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anti-Neuronal PAS Domain Protein 4 (NPAS4) (AA 445-585) antibody
NPAS4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neuronal PAS Domain Protein 4 (NPAS4) (AA 704-802) antibodyNPAS4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E4 unconjugated
anti-Neuronal PAS Domain Protein 4 (NPAS4) (Internal Region) antibodyVerified NPAS4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Neuronal PAS Domain Protein 4 (NPAS4) (AA 597-802) antibodyNPAS4 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S408-79 unconjugated
anti-Neuronal PAS Domain Protein 4 (NPAS4) (AA 597-802) antibody (HRP)NPAS4 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S408-79 HRP
anti-Neuronal PAS Domain Protein 4 (NPAS4) (AA 597-802) antibody (FITC)NPAS4 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S408-79 FITC
anti-Neuronal PAS Domain Protein 4 (NPAS4) (AA 597-802) antibody (Biotin)NPAS4 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S408-79 Biotin
anti-Neuronal PAS Domain Protein 4 (NPAS4) (AA 597-802) antibody (PE)NPAS4 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S408-79 PE
anti-Neuronal PAS Domain Protein 4 (NPAS4) (AA 597-802) antibody (APC)NPAS4 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S408-79 APC
anti-Neuronal PAS Domain Protein 4 (NPAS4) (AA 597-802) antibody (PerCP)NPAS4 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S408-79 PerCP
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))
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别名
- NPAS4
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背景
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Background: Transcription factor expressed in neurons of the brain that regulates the excitatory-inhibitory balance within neural circuits and is required for contextual memory in the hyppocampus (By similarity). Plays a key role in the structural and functional plasticity of neurons (By similarity). Acts as an early-response transcription factor in both excitatory and inhibitory neurons, where it induces distinct but overlapping sets of late-response genes in these two types of neurons, allowing the synapses that form on inhibitory and excitatory neurons to be modified by neuronal activity in a manner specific to their function within a circuit, thereby facilitating appropriate circuit responses to sensory experience (By similarity). In excitatory neurons, activates transcription of BDNF, which in turn controls the number of GABA-releasing synapses that form on excitatory neurons, thereby promoting an increased number of inhibitory synapses on excitatory neurons (By similarity). In inhibitory neurons, regulates a distinct set of target genes that serve to increase excitatory input onto somatostatin neurons, probably resulting in enhanced feedback inhibition within cortical circuits (By similarity). The excitatory and inhibitory balance in neurons affects a number of processes, such as short-term and long-term memory, acquisition of experience, fear memory, response to stress and social behavior (By similarity). Acts as a regulator of dendritic spine development in olfactory bulb granule cells in a sensory-experience-dependent manner by regulating expression of MDM2 (By similarity). Efficient DNA binding requires dimerization with another bHLH protein, such as ARNT, ARNT2 or BMAL1 (PubMed:14701734). Can activate the CME (CNS midline enhancer) element (PubMed:14701734).
Aliases: bHLH PAS type transcription factor NXF antibody, bHLHe79 antibody, Class E basic helix-loop-helix protein 79 antibody, HLH-PAS transcription factor NXF antibody, Le PAS antibody, limbic enhanced PAS protein antibody, neuronal PAS domain protein 4 antibody, Neuronal PAS domain-containing protein 4 antibody, Neuronal PAS4 antibody, NPAS4 antibody, NPAS4_HUMAN antibody, NXF antibody, PAS domain-containing protein 10 antibody, PASD10 antibody
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UniProt
- Q8IUM7
抗原
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