C19orf46 抗体 (AA 1-242)
Quick Overview for C19orf46 抗体 (AA 1-242) (ABIN7161174)
抗原
See all C19orf46 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-242
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Nesprin-4 protein (1-242AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- C19orf46 (Chromosome 19 Open Reading Frame 46 (C19orf46))
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别名
- SYNE4
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背景
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Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus.
Aliases: SYNE4 antibody, C19orf46 antibody, Nesprin-4 antibody, KASH domain-containing protein 4 antibody, KASH4 antibody, Nuclear envelope spectrin repeat protein 4 antibody
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UniProt
- Q8N205
抗原
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