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SIRT5 抗体 (AA 60-212)

This 兔 多克隆 anti-SIRT5 antibody specifically detects SIRT5 in IHC, ELISA 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7160870
发货至: 中国
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Quick Overview for SIRT5 抗体 (AA 60-212) (ABIN7160870)

抗原

See all SIRT5 抗体
SIRT5 (Sirtuin 5 (SIRT5))

适用

  • 92
  • 50
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  • 2
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宿主

  • 85
  • 13
  • 2
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克隆类型

  • 81
  • 21
多克隆

标记

  • 49
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This SIRT5 antibody is un-conjugated

应用范围

  • 78
  • 33
  • 30
  • 21
  • 13
  • 10
  • 7
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  • 5
  • 3
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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 16
    • 10
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    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
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    AA 60-212

    原理

    SIRT5 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human NAD-dependent protein deacylase sirtuin-5, mitochondrial protein (60-212AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SIRT5 (Sirtuin 5 (SIRT5))

    别名

    SIRT5

    背景

    Background: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693). Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting (PubMed:22076378, PubMed:24703693). Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species (PubMed:24140062). Modulates ketogenesis through the desuccinylation and activation of HMGCS2 (By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX.

    Aliases: NAD dependent deacetylase sirtuin 5 antibody, NAD dependent lysine demalonylase and desuccinylase sirtuin 5 mitochondrial antibody, NAD dependent protein deacylase sirtuin 5 mitochondrial antibody, NAD-dependent protein deacylase sirtuin-5, mitochondrial antibody, Regulatory protein SIR2 homolog 5 antibody, Silent mating type information regulation 2 S.cerevisiae homolog 5 antibody, Sir2 like 5 antibody, SIR2-like protein 5 antibody, SIR2L5 antibody, SIR5_HUMAN antibody, Sirt5 antibody, Sirtuin 5 antibody, Sirtuin type 5 antibody

    UniProt

    Q9NXA8

    途径

    SARS-CoV-2 Protein Interactome
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