METTL14 抗体 (AA 24-206)
Quick Overview for METTL14 抗体 (AA 24-206) (ABIN7160801)
抗原
See all METTL14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-206
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human N6-adenosine-methyltransferase subunit METTL14 protein (24-206AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- METTL14 (Methyltransferase Like 14 (METTL14))
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别名
- METTL14
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背景
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Background: N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5\'-[AG]GAC-3\' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability (PubMed:24316715, PubMed:24407421, PubMed:25719671). M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop. M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization (By similarity).
Aliases: KIAA1627 antibody, MET14_HUMAN antibody, Methyltransferase like 14 antibody, Methyltransferase-like protein 14 antibody, METTL14 antibody, N6-adenosine-methyltransferase subunit METTL14 antibody, OTTHUMP00000219837 antibody
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UniProt
- Q9HCE5
抗原
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