NAT8 抗体 (AA 64-227) (FITC)
Quick Overview for NAT8 抗体 (AA 64-227) (FITC) (ABIN7160714)
抗原
See all NAT8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 64-227
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human N-acetyltransferase 8 protein (64-227AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NAT8 (N-Acetyltransferase 8 (NAT8))
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别名
- NAT8
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背景
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Background: Acetylates the free alpha-amino group of cysteine S-conjugates to form mercapturic acids (PubMed:20392701). This is the final step in a major route for detoxification of a wide variety of reactive electrophiles which starts with their incorporation into glutathione S-conjugates. The glutathione S-conjugates are then further processed into cysteine S-conjugates and finally mercapturic acids which are water soluble and can be readily excreted in urine or bile. Alternatively, may have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1 (PubMed:24556617). May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (PubMed:19011241).
Aliases: acetyltransferase 2 antibody, ATase2 antibody, Camello, Xenopus, homolog of, 1 antibody, Camello-like protein 1 antibody, CML1 antibody, cysteinyl-conjugate N-acetyltransferase antibody, GLA antibody, Hcml1 antibody, kidney- and liver-specific gene product antibody, N-acetyltransferase 8 (camello like) antibody, N-acetyltransferase 8 (GCN5-related, putative) antibody, N-acetyltransferase 8 antibody, NAT8 antibody, NAT8_HUMAN antibody, Probable N-acetyltransferase 8 antibody, TSC501 antibody, TSC510 antibody
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UniProt
- Q9UHE5
抗原
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