MTM1 抗体 (AA 484-603)
Quick Overview for MTM1 抗体 (AA 484-603) (ABIN7160627)
抗原
See all MTM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 484-603
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Myotubularin protein (484-603AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MTM1 (Myotubularin 1 (MTM1))
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别名
- MTM1
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背景
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Background: Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.
Aliases: AF073996 antibody, CG2 antibody, CNM antibody, KIAA4176 antibody, mKIAA4176 antibody, Mtm antibody, Mtm1 antibody, MTM1_HUMAN antibody, MTMX antibody, Myotubular myopathy 1 antibody, Myotubularin antibody, XLMTM antibody
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UniProt
- Q13496
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途径
- Inositol Metabolic Process, Skeletal Muscle Fiber Development
抗原
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