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DMPK 抗体 (AA 243-424) (Biotin)

This anti-DMPK antibody is a 兔 多克隆 antibody detecting DMPK in ELISA. Suitable for 人.
产品编号 ABIN7160624
发货至: 中国

Quick Overview for DMPK 抗体 (AA 243-424) (Biotin) (ABIN7160624)

抗原

See all DMPK 抗体
DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

适用

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宿主

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克隆类型

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多克隆

标记

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This DMPK antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

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    AA 243-424

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Myotonin-protein kinase protein (243-424AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

    别名

    DMPK

    背景

    Background: Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeostasis. Phosphorylates PLN, a regulator of calcium pumps and may regulate sarcoplasmic reticulum calcium uptake in myocytes. May also phosphorylate FXYD1/PLM which is able to induce chloride currents. May also play a role in synaptic plasticity.

    Aliases: DM 1 antibody, DM antibody, DM kinase antibody, DM protein kinase antibody, DM-kinase antibody, DM1 antibody, DM1 protein kinase antibody, DM1PK antibody, DMK antibody, DMPK antibody, DMPK_HUMAN antibody, Dystrophia myotonica 1 antibody, Dystrophia myotonica protein kinase antibody, MDPK antibody, MT PK antibody, MT-PK antibody, Myotonic dystrophy associated protein kinase antibody, Myotonic dystrophy protein kinase antibody, Myotonin protein kinase A antibody, Myotonin protein kinase antibody, Myotonin-protein kinase antibody, Thymopoietin homolog antibody

    UniProt

    Q09013

    途径

    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development
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