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MYOC 抗体 (AA 183-294)

MYOC 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7160496
发货至: 中国
  • 抗原 See all MYOC 抗体
    MYOC (Myocilin (MYOC))
    抗原表位
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 183-294
    适用
    • 30
    • 16
    • 16
    • 6
    • 2
    宿主
    • 26
    • 4
    克隆类型
    • 27
    • 3
    多克隆
    标记
    • 16
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYOC antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 10
    • 10
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Myocilin protein (183-294AA)
    亚型
    IgG
    Top Product
    Discover our top product MYOC Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MYOC (Myocilin (MYOC))
    别名
    MYOC (MYOC 产品)
    别名
    MYOC antibody, MGC136645 antibody, zgc:136645 antibody, AI957332 antibody, GLC1A antibody, TIGR antibody, GPOA antibody, JOAG antibody, JOAG1 antibody, myocilin antibody, Tigr antibody, myocilin antibody, MYOC antibody, myoc antibody, Myoc antibody
    背景

    Background: Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling. Plays a role in bone formation and promotes osteoblast differentiation in a dose-dependent manner through mitogen-activated protein kinase signaling. Mediates myelination in the peripheral nervous system through ERBB2/ERBB3 signaling. Plays a role as a regulator of muscle hypertrophy through the components of dystrophin-associated protein complex. Involved in positive regulation of mitochondrial depolarization. Plays a role in neurite outgrowth. May participate in the obstruction of fluid outflow in the trabecular meshwork.

    Aliases: GLC1A antibody, GPOA antibody, JOAG antibody, JOAG1 antibody, Mutated trabecular meshwork-induced glucocorticoid response protein antibody, MYOC antibody, MYOC_HUMAN antibody, Myocilin antibody, Myocilin, trabecular meshwork inducible glucocorticoid antibody, TIGR antibody, Trabecular meshwork induced glucocorticoid response protein antibody, Trabecular meshwork-induced glucocorticoid response protein antibody

    UniProt
    Q99972
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