电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MBNL1 抗体 (AA 1-382)

This 兔 多克隆 anti-MBNL1 antibody specifically detects MBNL1 in ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7160357
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MBNL1 抗体 (AA 1-382) (ABIN7160357)

抗原

See all MBNL1 抗体
MBNL1 (Muscleblind-like Protein 1 (MBNL1))

适用

  • 37
  • 5
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 30
  • 6
  • 1

克隆类型

  • 29
  • 8
多克隆

标记

  • 25
  • 4
  • 3
  • 3
  • 1
  • 1
This MBNL1 antibody is un-conjugated

应用范围

  • 34
  • 21
  • 7
  • 7
  • 3
  • 3
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 9
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-382

    原理

    MBNL1 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Muscleblind-like protein 1 protein (1-382AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MBNL1 (Muscleblind-like Protein 1 (MBNL1))

    别名

    MBNL1

    背景

    Background: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5\'-YGCU(U/G)Y-3\'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.

    Aliases: EXP antibody, EXP35 antibody, EXP40 antibody, EXP42 antibody, KIAA0428 antibody, MBNL antibody, MBNL protein antibody, MBNL1 antibody, MBNL1_HUMAN antibody, Muscleblind 41kD isoform antibody, Muscleblind like antibody, Muscleblind like protein 1 antibody, Muscleblind like splicing regulator 1 antibody, Muscleblind-like protein 1 antibody, Triplet expansion RNA binding protein antibody, Triplet-expansion RNA-binding protein antibody

    UniProt

    Q9NR56

    途径

    Ribonucleoprotein Complex Subunit Organization
You are here: