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SMAD7 抗体 (AA 36-247) (HRP)

This anti-SMAD7 antibody is a 兔 多克隆 antibody detecting SMAD7 in ELISA. Suitable for 人.
产品编号 ABIN7160249
发货至: 中国

Quick Overview for SMAD7 抗体 (AA 36-247) (HRP) (ABIN7160249)

抗原

See all SMAD7 抗体
SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

适用

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宿主

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克隆类型

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多克隆

标记

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This SMAD7 antibody is conjugated to HRP

应用范围

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ELISA
  • 抗原表位

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    AA 36-247

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Mothers against decapentaplegic homolog 7 protein (36-247AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

    别名

    SMAD7

    背景

    Background: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

    Aliases: CRCS3 antibody, FLJ16482 antibody, hSMAD 7 antibody, hSMAD7 antibody, MAD (mothers against decapentaplegic Drosophila) homolog 7 antibody, MAD antibody, Mad homolog 7 antibody, MAD homolog 8 antibody, MAD mothers against decapentaplegic homolog 7 antibody, MADH 7 antibody, MADH 8 antibody, MADH6 antibody, MADH7 antibody, MADH8 antibody, Mothers Against Decapentaplegic Drosophila Homolog of 6 antibody, Mothers Against Decapentaplegic Drosophila Homolog of 7 antibody, Mothers against decapentaplegic homolog 7 antibody, Mothers against decapentaplegic homolog 8 antibody, Mothers against DPP homolog 7 antibody, Mothers against DPP homolog 8 antibody, SMA- AND MAD-RELATED PROTEIN 7 antibody, SMAD 7 antibody, SMAD antibody, SMAD family member 7 antibody, SMAD, mothers against DPP homolog 7 (Drosophila) antibody, SMAD, mothers against DPP homolog 7 antibody, SMAD6 antibody, Smad7 antibody, SMAD7_HUMAN antibody

    UniProt

    O15105

    途径

    Interferon-gamma Pathway, Cell-Cell Junction Organization
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