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MORF4L1 抗体 (AA 1-100)

This anti-MORF4L1 antibody is a 兔 多克隆 antibody detecting MORF4L1 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7160219
发货至: 中国

Quick Overview for MORF4L1 抗体 (AA 1-100) (ABIN7160219)

抗原

See all MORF4L1 抗体
MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

适用

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宿主

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克隆类型

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多克隆

标记

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This MORF4L1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-100

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Mortality factor 4-like protein 1 protein (1-100AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

    别名

    MORF4L1

    背景

    Background: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.

    Aliases: CG6363 antibody, Eaf3 antibody, Esa1p associated factor 3 homolog antibody, FWP006 antibody, HsT17725 antibody, MEAF3 antibody, MO4L1_HUMAN antibody, MORF related gene on chromosome 15 antibody, MORF-related gene 15 protein antibody, Morf4l1 antibody, MORFRG15 antibody, Mortality factor 4 like 1 antibody, Mortality factor 4 like protein 1 antibody, Mortality factor 4-like protein 1 antibody, MRG15 antibody, Protein MSL3-1 antibody, S863-6 antibody, Transcription factor-like protein MRG15 antibody

    UniProt

    Q9UBU8

    途径

    Chromatin Binding
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