C20orf72 抗体 (AA 81-260)
Quick Overview for C20orf72 抗体 (AA 81-260) (ABIN7159874)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-260
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Mitochondrial genome maintenance exonuclease 1 protein (81-260AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
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别名
- MGME1
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背景
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Background: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5\'-3\' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
Aliases: MGME1 antibody, C20orf72 antibody, DDK1Mitochondrial genome maintenance exonuclease 1 antibody, EC 3.1.-.- antibody
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UniProt
- Q9BQP7
抗原
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