H13 抗体 (AA 336-377)
Quick Overview for H13 抗体 (AA 336-377) (ABIN7159822)
抗原
See all H13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 336-377
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Minor histocompatibility antigen H13 protein (336-377AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- H13 (Histocompatibility 13 (H13))
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别名
- HM13
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背景
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Background: Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides (PubMed:11714810). May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein (PubMed:12145199). Involved in the intramembrane cleavage of the integral membrane protein PSEN1 (PubMed:12077416, PubMed:11714810, PubMed:14741365). Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139-dependent manner (PubMed:25239945). May play a role in graft rejection (By similarity).
Aliases: dJ324O17.1 antibody, H13 antibody, hIMP1 antibody, Histocompatibility (minor) 13 antibody, HM13 antibody, HM13_HUMAN antibody, IMP-1 antibody, IMP1 antibody, IMPAS antibody, IMPAS-1 antibody, Intramembrane protease 1 antibody, Intramembrane protease antibody, Minor histocompatibility antigen 13 antibody, Minor histocompatibility antigen H13 antibody, MSTP086 antibody, OTTHUMP00000030527 antibody, OTTHUMP00000030528 antibody, OTTHUMP00000030530 antibody, OTTHUMP00000214528 antibody, Presenilin-like protein 3 antibody, PSENL3 antibody, PSL3 antibody, Signal peptide peptidase antibody, Signal peptide peptidase beta antibody, SPP antibody
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UniProt
- Q8TCT9
抗原
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