MACF1 抗体 (AA 1936-2150)
Quick Overview for MACF1 抗体 (AA 1936-2150) (ABIN7159742)
抗原
See all MACF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1936-2150
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 protein (1936-2150AA)
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亚型
- IgG
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anti-Microtubule-Actin Crosslinking Factor 1 (MACF1) (AA 1-95) antibody
MACF1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1G9 unconjugated
anti-Microtubule-Actin Crosslinking Factor 1 (MACF1) (AA 1-95) antibodyMACF1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))
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别名
- MACF1
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背景
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Background: Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells (By similarity).
Aliases: MACF1 antibody, ABP620 antibody, ACF7 antibody, KIAA0465 antibody, KIAA1251 antibody, Microtubule-actin cross-linking factor 1 antibody, isoforms 1/2/3/5 antibody, 620 kDa actin-binding protein antibody, ABP620 antibody, Actin cross-linking family protein 7 antibody, Macrophin-1 antibody, Trabeculin-alpha antibody
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UniProt
- Q9UPN3
抗原
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