APOO 抗体 (AA 26-198)
Quick Overview for APOO 抗体 (AA 26-198) (ABIN7159688)
抗原
See all APOO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-198
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human MICOS complex subunit MIC26 protein (26-198AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- APOO (Apolipoprotein O (APOO))
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别名
- APOO
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背景
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Background: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:25764979). Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts (PubMed:24743151). Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL (PubMed:16956892).
Aliases: 0610008C08Rik antibody, 1110019O03Rik antibody, Apolipoprotein O antibody, APOO antibody, APOO_HUMAN antibody, FAM121B antibody, Family with sequence similarity 121B antibody, MGC130105 antibody, MGC130106 antibody, MGC4825 antibody, My025 antibody, MYO25 antibody, OTTHUMP00000023073 antibody, Protein FAM121B antibody, RP23-272D10.2 antibody
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UniProt
- Q9BUR5
抗原
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