METRNL 抗体 (AA 46-311)
Quick Overview for METRNL 抗体 (AA 46-311) (ABIN7159569)
抗原
See all METRNL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 46-311
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Meteorin-like protein (46-311AA)
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亚型
- IgG
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anti-Meteorin, Glial Cell Differentiation Regulator-Like (METRNL) (AA 46-311) antibody
METRNL 适用: 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Meteorin, Glial Cell Differentiation Regulator-Like (METRNL) (N-Term) antibodyMETRNL 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Meteorin, Glial Cell Differentiation Regulator-Like (METRNL) (C-Term) antibodyMETRNL 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
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别名
- METRNL
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背景
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Background: Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures.
Aliases: Meteorin like glial cell differentiation regulator antibody, Meteorin, glial cell differentiation regulator like antibody, Meteorin-like protein antibody, METRL_HUMAN antibody, Metrnl antibody
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UniProt
- Q641Q3
抗原
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