STEAP1 抗体 (AA 3-69)
Quick Overview for STEAP1 抗体 (AA 3-69) (ABIN7159501)
抗原
See all STEAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-69
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Metalloreductase STEAP1 protein (3-69AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
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别名
- STEAP1
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背景
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Background: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis By similarity. Mediates \\\'Lys-63\\\'-linked polyubiquitination of TBK1, which probably participates in kinase activation.
Aliases: 2410007B19Rik antibody, EC 1.16.1.- antibody, Metalloreductase STEAP1 antibody, MGC19484 antibody, PRSS 24 antibody, PRSS24 antibody, Six transmembrane epithelial antigen of prostate antibody, Six transmembrane epithelial antigen of the prostate 1 antibody, Six transmembrane epithelial antigen of the prostate antibody, Six-transmembrane epithelial antigen of prostate 1 antibody, STEA1_HUMAN antibody, STEAP 1 antibody, Steap antibody, STEAP1 antibody
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UniProt
- Q9UHE8
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途径
- Transition Metal Ion Homeostasis
抗原
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