PKMYT1 抗体 (AA 900-1101)
Quick Overview for PKMYT1 抗体 (AA 900-1101) (ABIN7159368)
抗原
See all PKMYT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 900-1101
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase protein (900-1101AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))
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别名
- PKMYT1
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背景
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Background: Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on \'Thr-14\'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on \'Tyr-15\' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.
Aliases: cdc2 inhibitory kinase antibody, DKFZp547K1610 antibody, FLJ20093 antibody, Membrane associated tyrosine and threonine specific cdc2 inhibitory kinase antibody, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase antibody, MYT1 antibody, Myt1 kinase antibody, PKMYT 1 antibody, Pkmyt1 antibody, PMYT1_HUMAN antibody, PPP1R126 antibody, Protein kinase membrane associated tyrosine/threonine 1 antibody, Protein kinase Myt1 antibody, Protein phosphatase 1 regulatory subunit 126 antibody
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UniProt
- Q99640
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途径
- Mitotic G1-G1/S Phases, M Phase
抗原
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