MED12 抗体 (AA 1742-2011)
Quick Overview for MED12 抗体 (AA 1742-2011) (ABIN7159104)
抗原
See all MED12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1742-2011
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Mediator of RNA polymerase II transcription subunit 12 protein (1742-2011AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MED12 (Mediator Complex Subunit 12 (MED12))
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别名
- MED12
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背景
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Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
Aliases: Activator recruited cofactor 240 kDa component antibody, Activator-recruited cofactor 240 kDa component antibody, ARC240 antibody, CAG repeat protein 45 antibody, CAGH45 antibody, HOPA antibody, KIAA0192 antibody, MED12 antibody, MED12_HUMAN antibody, Mediator complex subunit 12 antibody, Mediator of RNA polymerase II transcription subunit 12 antibody, OPA containing protein antibody, OPA-containing protein antibody, Thyroid hormone receptor associated protein complex 230 kDa component antibody, Thyroid hormone receptor-associated protein complex 230 kDa component antibody, TNRC11 antibody, Trap230 antibody, Trinucleotide repeat containing gene 11 protein antibody, Trinucleotide repeat-containing gene 11 protein antibody
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UniProt
- Q93074
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation
抗原
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