MED1 抗体 (AA 878-1031) (FITC)
Quick Overview for MED1 抗体 (AA 878-1031) (FITC) (ABIN7159102)
抗原
See all MED1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 878-1031
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Mediator of RNA polymerase II transcription subunit 1 protein (878-1031AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MED1 (Mediator Complex Subunit 1 (MED1))
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别名
- MED1
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背景
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Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (PubMed:10406464, PubMed:11867769, PubMed:12037571, PubMed:12218053, PubMed:12556447, PubMed:14636573, PubMed:15340084, PubMed:15471764, PubMed:15989967, PubMed:16574658, PubMed:9653119). Acts as a coactivator for GATA1-mediated transcriptional activation during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781).
Aliases: Activator-recruited cofactor 205 kDa component antibody, ARC205 antibody, CRSP1 antibody, CRSP200 antibody, DRIP205 antibody, DRIP230 antibody, MED1 antibody, MED1_HUMAN antibody, Mediator complex subunit 1 antibody, Mediator of RNA polymerase II transcription subunit 1 antibody, p53 regulatory protein RB18A antibody, PBP antibody, Peroxisome proliferator-activated receptor-binding protein antibody, PPAR binding protein antibody, PPAR-binding protein antibody, PPARBP antibody, PPARGBP antibody, RB18A antibody, Thyroid hormone receptor-associated protein complex 220 kDa component antibody, Thyroid receptor-interacting protein 2 antibody, TR-interacting protein 2 antibody, Trap220 antibody, TRIP-2 antibody, TRIP2 antibody, Vitamin D receptor-interacting protein complex component DRIP205 antibody
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UniProt
- Q15648
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途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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