MRGPRX2 抗体 (AA 286-330)
Quick Overview for MRGPRX2 抗体 (AA 286-330) (ABIN7159013)
抗原
See all MRGPRX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 286-330
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Mas-related G-protein coupled receptor member X2 protein (286-330AA)
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亚型
- IgG
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anti-G Protein-Coupled Receptor MRGX2 (MRGPRX2) (Extracellular Domain) antibody
MRGPRX2 适用: 人, 猴 IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor MRGX2 (MRGPRX2) (AA 1-330) antibodyMRGPRX2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein-Coupled Receptor MRGX2 (MRGPRX2) (AA 287-315) antibodyMRGPRX2 适用: 人 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
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别名
- MRGPRX2
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背景
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Background: Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.
Aliases: G protein coupled receptor MRGX 2 antibody, G protein coupled receptor MRGX2 antibody, Mas related G protein coupled receptor member X2 antibody, Mas related gene MRGX 2 antibody, Mas related gene MRGX2 antibody, MAS related GPR member X2 antibody, Mas-related G-protein coupled receptor member X antibody, Mas-related G-protein coupled receptor member X2 antibody, MRGPRX 2 antibody, MRGPRX2 antibody, MRGX 2 antibody, MRGX2 antibody, MRGX2_HUMAN antibody
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UniProt
- Q96LB1
抗原
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