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PRNP 抗体 (AA 23-64) (HRP)

This anti-PRNP antibody is a 兔 多克隆 antibody detecting PRNP in ELISA. Suitable for 人.
产品编号 ABIN7158935
发货至: 中国

Quick Overview for PRNP 抗体 (AA 23-64) (HRP) (ABIN7158935)

抗原

See all PRNP 抗体
PRNP (Prion Protein (PRNP))

适用

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宿主

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克隆类型

  • 81
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多克隆

标记

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This PRNP antibody is conjugated to HRP

应用范围

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ELISA
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    AA 23-64

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Major prion protein (23-64AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PRNP (Prion Protein (PRNP))

    别名

    PRNP

    背景

    Background: Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as a agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).

    Aliases: Alternative prion protein, major prion protein antibody, AltPrP antibody, ASCR antibody, CD230 antibody, CD230 antigen antibody, CJD antibody, GSS antibody, KURU antibody, Major prion protein antibody, p27 30 antibody, PRIO_HUMAN antibody, Prion protein antibody, Prion related protein antibody, PRIP antibody, PRNP antibody, PrP antibody, PrP27 30 antibody, PrP27-30 antibody, PrP33-35C antibody, PrPC antibody, PrPSc antibody, Sinc antibody

    UniProt

    P04156

    途径

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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