LOXL2 抗体 (AA 27-121)
Quick Overview for LOXL2 抗体 (AA 27-121) (ABIN7158837)
抗原
See all LOXL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-121
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Lysyl oxidase homolog 2 protein (27-121AA)
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亚型
- IgG
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anti-Lysyl Oxidase-Like 2 (LOXL2) antibody
KO Validated LOXL2 适用: 人 WB, IHC, ELISA, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 544-751) antibodyLOXL2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) antibodyLOXL2 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Monoclonal 2E5 unconjugated Recombinant Antibody
anti-Lysyl Oxidase-Like 2 (LOXL2) (Internal Region) antibodyLOXL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 675-773) antibodyLOXL2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5D2 unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 53-160) antibodyLOXL2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 675-773) antibodyLOXL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 505-774) antibodyLOXL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 553-761) antibodyLOXL2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 434-546) antibodyLOXL2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
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别名
- LOXL2
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背景
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Background: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated \\\'Lys-4\\\' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of E-cadherin, probably by mediating deamination of histone H3. Also involved in E-cadherin repression following hypoxia, a hallmark of epithelial to mesenchymal transition believed to amplify tumor aggressiveness, suggesting that it may play a role in tumor progression. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.
Aliases: LOR 2 antibody, LOR2 antibody, LOX L2 antibody, LOXL 2 antibody, LOXL2 antibody, LOXL2_HUMAN antibody, Lysyl oxidase homolog 2 antibody, Lysyl oxidase like 2 antibody, Lysyl oxidase like protein 2 antibody, Lysyl oxidase related 2 antibody, Lysyl oxidase related protein 2 antibody, Lysyl oxidase related protein WS9 14 antibody, Lysyl oxidase-like protein 2 antibody, Lysyl oxidase-related protein 2 antibody, Lysyl oxidase-related protein WS9-14 antibody, WS9 14 antibody
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UniProt
- Q9Y4K0
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途径
- Chromatin Binding
抗原
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