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KDM6A 抗体 (AA 620-749)

This anti-KDM6A antibody is a 兔 多克隆 antibody detecting KDM6A in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7158716
发货至: 中国

Quick Overview for KDM6A 抗体 (AA 620-749) (ABIN7158716)

抗原

See all KDM6A 抗体
KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

适用

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宿主

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克隆类型

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多克隆

标记

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This KDM6A antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 620-749

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Lysine-specific demethylase 6A protein (620-749AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:200-1:500,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

    别名

    KDM6A

    背景

    Background: Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code (PubMed:17851529, PubMed:17713478, PubMed:17761849). Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27' (PubMed:17851529, PubMed:17713478, PubMed:17761849). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (PubMed:17761849).

    Aliases: bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX) antibody, bA386N14.2 antibody, bA386N14.2 ubiquitously transcribed X chromosome tetratricopeptide repeat protein UTX antibody, DKFZp686A03225 antibody, Histone demethylase UTX antibody, KABUK2 antibody, Kdm6a antibody, KDM6A_HUMAN antibody, Lysine (K) specific demethylase 6A antibody, Lysine K specific demethylase 6A antibody, Lysine specific demethylase 6A ubiquitously transcribed tetratricopeptide repeat gene X chromosome antibody, Lysine-specific demethylase 6A antibody, MGC141941 antibody, Ubiquitously transcribed tetratricopeptide repeat X chromosome antibody, Ubiquitously transcribed tetratricopeptide repeat protein X linked antibody, Ubiquitously transcribed TPR gene on the X chromosome antibody, Ubiquitously transcribed TPR protein on the X chromosome antibody, Ubiquitously transcribed X chromosome tetratricopeptide repeat protein antibody, Ubiquitously-transcribed TPR protein on the X chromosome antibody, Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein antibody, UTX antibody

    UniProt

    O15550

    途径

    Tube Formation, Warburg Effect
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