KDM2B 抗体 (AA 1274-1336) (Biotin)
Quick Overview for KDM2B 抗体 (AA 1274-1336) (Biotin) (ABIN7158692)
抗原
See all KDM2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1274-1336
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Lysine-specific demethylase 2B protein (1274-1336AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))
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别名
- KDM2B
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背景
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Background: Histone demethylase that demethylates \'Lys-4\' and \'Lys-36\' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 \'Lys-4\' and dimethylated H3 \'Lys-36\' residue while it has weak or no activity for mono- and tri-methylated H3 \'Lys-36\'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Aliases: [Histone-H3]-lysine-36 demethylase 1B antibody, CXXC-type zinc finger protein 2 antibody, CXXC2 antibody, F box and leucine rich repeat protein 10 antibody, F box protein FBL10 antibody, F-box and leucine-rich repeat protein 10 antibody, F-box protein FBL10 antibody, F-box/LRR-repeat protein 10 antibody, Fbl10 antibody, FBXL10 antibody, JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein antibody, JHDM1B antibody, JmjC domain-containing histone demethylation protein 1B antibody, Jumonji C domain containing histone demethylase 1B antibody, Jumonji domain-containing EMSY-interactor methyltransferase motif protein antibody, kdm2b antibody, KDM2B_HUMAN antibody, Lysine (K) specific demethylase 2B antibody, Lysine-specific demethylase 2B antibody, PCCX2 antibody, Protein containing CXXC domain 2 antibody, Protein JEMMA antibody, Protein-containing CXXC domain 2 antibody
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UniProt
- Q8NHM5
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途径
- Tube Formation, Warburg Effect
抗原
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